Journal of Contemporary Issues in Business and Government


Print ISSN: 2204-1990

Online ISSN: 1323-6903

Volume26, Issue2

Preference Of Analgesic Drug For Pain Control Following Extraction Of Teeth - A Retrospective Study

Journal of Contemporary Issues in Business and Government, 2020, Volume 26, Issue 2, Pages 387-393
10.47750/cibg.2020.26.02.048

Abstract

The aim of this retroperspective study was to assess the preference of analgesic drugs administered for pain control following dental extraction of teeth. The study was conducted in a  University based setting.The study group of this research were patients who reported to the clinics with moderate to severe toothache/ dental pain who required tooth extraction.Case sheets were reviewed between June 2019 to March 2020.Data were analyzed using SPSS software (IBM SPSS Statistics, Version 24.0, Armonk, NY: IBM Corp).  Chi square test was applied to find the association between the parameters and the level of significance.A total of 7888 patients were involved in this study.  45.7% were female patients and 54.3% were male patients. About 70.3% of the population falls in the age category 21-60 years.Around 45.8% of the population were prescribed with Paracetamol. The commonly prescribed combination analgesic of choice was Paracetamol and Aceclofenac for  26.6%  of the patients. We conclude that middle aged patients in the age group 21-60 years were prescribed Paracetamol as the first analgesic of choice for postoperative dental pain control.
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  1. Abhinav, R. P. et al. (2019) ‘The Patterns and Etiology of Maxillofacial Trauma in South India’, Annals of maxillofacial surgery, 9(1), pp. 114–117.
  2. Abraham, S. et al. (2005) ‘Evaluation of the inhibitory effect of triphala on PMN-type matrix metalloproteinase (MMP-9)’, Journal of periodontology, 76(4), pp. 497–502.
  3. Acs, G. et al. (1986) ‘The incidence of post-extraction pain and analgesic usage in children’, Anesthesia progress, 33(3), pp. 147–151.
  4. Ahlström, U. et al. (1993) ‘The analgesic efficacy of diclofenac dispersible and ibuprofen in postoperative pain after dental extraction’, European journal of clinical pharmacology, 44(6), pp. 587–588.
  5. Arja, C. et al. (2013) ‘Oxidative stress and antioxidant enzyme activity in South Indian male smokers with chronic obstructive pulmonary disease’, Respirology , 18(7), pp. 1069–1075.
  6. Au, A. H. Y. et al. (2015) ‘The Efficacy and Clinical Safety of Various Analgesic Combinations for Post-Operative Pain after Third Molar Surgery: A Systematic Review and Meta-Analysis’, PloS one, 10(6), p. e0127611.
  7. Au, H.-Y. (no date) ‘The efficacy and clinical safety of various analgesic combinations for post-operative dental pain’. doi: 10.5353/th_b5063957.
  8. Barden, J. et al. (2004) ‘Relative efficacy of oral analgesics after third molar extraction’, British dental journal, 197(7), pp. 407–11; discussion 397.
  9. Bryce, G., Bomfim, D. I. and Bassi, G. S. (2014) ‘Pre- and post-operative management of dental implant placement. Part 1: management of post-operative pain’, British Dental Journal, pp. 123–127. doi: 10.1038/sj.bdj.2014.650.
  10. Chen, Y. and Chen, D. (2015) ‘Analgesic Effect Observation of Shixin Buccal Tablets on Pericoronitis of Wisdom Tooth’, China Pharmacy, (29), pp. 4110–4111.
  11. Christabel, A. et al. (2016) ‘Comparison of pterygomaxillary dysjunction with tuberosity separation in isolated Le Fort I osteotomies: a prospective, multi-centre, triple-blind, randomized controlled trial’, International journal of oral and maxillofacial surgery, 45(2), pp. 180–185.
  12. Derry, S., Wiffen, P. J. and Moore, R. A. (2011) ‘Relative efficacy of oral analgesics after third molar extraction – a 2011 update’, British Dental Journal, pp. 419–420. doi: 10.1038/sj.bdj.2011.905.
  13. Devaki, T., Sathivel, A. and BalajiRaghavendran, H. R. (2009) ‘Stabilization of mitochondrial and microsomal function by polysaccharide of Ulva lactuca on D-Galactosamine induced hepatitis in rats’, Chemico-biological interactions, 177(2), pp. 83–88.
  14. Edward Wallis, C. (1909) An Atlas of Dental Extractions with Notes on the Causes and Relief of Dental Pain. J. & A. Churchill.
  15. Ezhilarasan, D. (2018) ‘Oxidative stress is bane in chronic liver diseases: Clinical and experimental perspective’, Arab journal of gastroenterology: the official publication of the Pan-Arab Association of Gastroenterology, 19(2), pp. 56–64.
  16. Ezhilarasan, D., Sokal, E. and Najimi, M. (2018) ‘Hepatic fibrosis: It is time to go with hepatic stellate cell-specific therapeutic targets’, Hepatobiliary & pancreatic diseases international: HBPD INT, 17(3), pp. 192–197.
  17. Folayan, M. O. et al. (2014) ‘Non‑third molar related pericoronitis in a sub‑urban Nigeria population of children’, Nigerian journal of clinical practice, 17(1), pp. 18–22.
  18. Forbes, J. A. et al. (1990) ‘Evaluation of ketorolac, ibuprofen, acetaminophen, and an acetaminophen-codeine combination in postoperative oral surgery pain’, Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 10(6P2), p. 94S–105S.
  19. Gottschalk, A. and Smith, D. S. (2001) ‘New concepts in acute pain therapy: preemptive analgesia’, American family physician, 63(10), pp. 1979–1984.
  20. Hanzawa, A. et al. (2018) ‘A Comparative Study of Oral Analgesics for Postoperative Pain After Minor Oral Surgery’, Anesthesia progress, 65(1), pp. 24–29.
  21. Hersh, E. V. et al. (2020) ‘Nonsteroidal Anti-Inflammatory Drugs and Opioids in Postsurgical Dental Pain’, Journal of dental research, p. 22034520914254.
  22. Hyllested, M. et al. (2002) ‘Comparative effect of paracetamol, NSAIDs or their combination in postoperative pain management: a qualitative review’, British journal of anaesthesia, 88(2), pp. 199–214.
  23. Jain, A. K. et al. (1986) ‘Analgesic efficacy of low-dose ibuprofen in dental extraction pain’, Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 6(6), pp. 318–322.
  24. Jain, S. V. et al. (2019) ‘Evaluation of three-dimensional changes in pharyngeal airway following isolated lefort one osteotomy for the correction of vertical maxillary excess: a prospective study’, Journal of maxillofacial and oral surgery, 18(1), pp. 139–146.
  25. Jesudasan, J. S., Wahab, P. U. A. and Sekhar, M. R. M. (2015) ‘Effectiveness of 0.2% chlorhexidine gel and a eugenol-based paste on postoperative alveolar osteitis in patients having third molars extracted: a randomised …’, British Journal of Oral and. Available at: https://www.sciencedirect.com/science/article/pii/S0266435615002314.
  26. Joshi, A., Parara, E. and Macfarlane, T. V. (2004) ‘A double-blind randomised controlled clinical trial of the effect of preoperative ibuprofen, diclofenac, paracetamol with codeine and placebo tablets for relief of postoperative pain after removal of impacted third molars’, British Journal of Oral and Maxillofacial Surgery, pp. 299–306. doi: 10.1016/j.bjoms.2004.02.004.
  27. J, P. C. et al. (2018) ‘Prevalence and measurement of anterior loop of the mandibular canal using CBCT: A cross sectional study’, Clinical implant dentistry and related research, 20(4), pp. 531–534.
  28. Kaklamanos, E. G., Makrygiannakis, M. A. and Athanasiou, A. E. (2020) ‘Do analgesics used for the pain experienced after orthodontic procedures affect tooth movement rate? A systematic review based on animal studies’, Orthodontics & craniofacial research, 23(2), pp. 143–150.
  29. Krishnaswamy, H. et al. (2020) ‘Investigation of air conditioning temperature variation by modifying the structure of passenger car using computational fluid dynamics’, Thermal Science, 24(1 Part B), pp. 495–498.
  30. Kumar, S. (2017a) ‘RELATIONSHIP BETWEEN DENTAL ANXIETY AND PAIN EXPERIENCE DURING DENTAL EXTRACTIONS’, Asian Journal of Pharmaceutical and Clinical Research, p. 458. doi: 10.22159/ajpcr.2017.v10i3.16518.
  31. Kumar, S. (2017b) ‘THE EMERGING ROLE OF BOTULINUM TOXIN IN THE TREATMENT OF OROFACIAL DISORDERS: LITERATURE UPDATE’, Asian Journal of Pharmaceutical and Clinical Research, p. 21. doi: 10.22159/ajpcr.2017.v10i9.16914.
  32. Kumar, S. and Rahman, R. (2017) ‘KNOWLEDGE, AWARENESS, AND PRACTICES REGARDING BIOMEDICAL WASTE MANAGEMENT AMONG UNDERGRADUATE DENTAL STUDENTS’, Asian Journal of Pharmaceutical and Clinical Research, p. 341. doi: 10.22159/ajpcr.2017.v10i8.19101.
  33. Kumar, S. and Sneha, S. (2016) ‘KNOWLEDGE AND AWARENESS REGARDING ANTIBIOTIC PROPHYLAXIS FOR INFECTIVE ENDOCARDITIS AMONG UNDERGRADUATE DENTAL STUDENTS’, Asian Journal of Pharmaceutical and Clinical Research, p. 154. doi: 10.22159/ajpcr.2016.v9s2.13405.
  34. Maldonado, C. (2017) Pain Relief: From Analgesics to Alternative Therapies. BoD – Books on Demand.
  35. Malli Sureshbabu, N. et al. (2019) ‘Concentrated Growth Factors as an Ingenious Biomaterial in Regeneration of Bony Defects after Periapical Surgery: A Report of Two Cases’, Case reports in dentistry, 2019, p. 7046203.
  36. Manivannan, I. et al. (2017) ‘Tribological and surface behavior of silicon carbide reinforced aluminum matrix nanocomposite’, Surfaces and Interfaces, 8, pp. 127–136.
  37. Marimuthu, M. et al. (2018) ‘Canonical Wnt pathway gene expression and their clinical correlation in oral squamous cell carcinoma’, Indian journal of dental research: official publication of Indian Society for Dental Research, 29(3), pp. 291–297.
  38. Mehta, M. et al. (2019) ‘Oligonucleotide therapy: An emerging focus area for drug delivery in chronic inflammatory respiratory diseases’, Chemico-biological interactions, 308, pp. 206–215.
  39. Moore, P. A. et al. (1998) ‘Tramadol hydrochloride: analgesic efficacy compared with codeine, aspirin with codeine, and placebo after dental extraction’, Journal of clinical pharmacology, 38(6), pp. 554–560.
  40. Mp, S. K. (2017) ‘The emerging role of botulinum toxin in the treatment of orofacial disorders: Literature update’, Asian J Pharm Clin Res. Available at: https://innovareacademics.org/journals/index.php/ajpcr/article/download/16914/12228.
  41. Nalliah, R. P. et al. (2020) ‘Association of Opioid Use With Pain and Satisfaction After Dental Extraction’, JAMA network open, 3(3), p. e200901.
  42. Neelakantan, P. et al. (2010) ‘Root and Canal Morphology of Mandibular Second Molars in an Indian Population’, Journal of endodontics, 36(8), pp. 1319–1322.
  43. Neelakantan, P. et al. (2015) ‘Photoactivation of curcumin and sodium hypochlorite to enhance antibiofilm efficacy in root canal dentin’, Photodiagnosis and photodynamic therapy, 12(1), pp. 108–114.
  44. Packiri, S., Gurunathan, D. and Selvarasu, K. (2017) ‘Management of Paediatric Oral Ranula: A Systematic Review’, Journal of clinical and diagnostic research: JCDR, 11(9), pp. ZE06–ZE09.
  45. Patil, S. B. et al. (2017) ‘Comparison of Extended Nasolabial Flap Versus Buccal Fat Pad Graft in the Surgical Management of Oral Submucous Fibrosis: A Prospective Pilot Study’, Journal of maxillofacial and oral surgery, 16(3), pp. 312–321.
  46. Patturaja, K. and Pradeep, D. (2016) ‘Awareness of Basic Dental Procedure among General Population’, Research Journal of Pharmacy and Technology, 9(9), pp. 1349–1351.
  47. Piot, B. et al. (2002) ‘Management of dental extractions in patients with bleeding disorders’, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 93(3), pp. 247–250.
  48. Raffaeli, G. et al. (2016) ‘Fever and Pain Management in Childhood: Healthcare Providers’ and Parents' Adherence to Current Recommendations’, International journal of environmental research and public health, 13(5). doi: 10.3390/ijerph13050499.
  49. Rahman, R. and Mp, S. K. (2017) ‘KNOWLEDGE, ATTITUDE, AND AWARENESS OF DENTAL UNDERGRADUATE STUDENTS REGARDING HUMAN IMMUNODEFICIENCY VIRUS/ACQUIRED IMMUNODEFICIENCY SYNDROME PATIENTS’, Asian J Pharm Clin Res, 10(5), pp. 175–180.
  50. Ramamoorthi, S., Nivedhitha, M. S. and Divyanand, M. J. (2015) ‘Comparative evaluation of postoperative pain after using endodontic needle and EndoActivator during root canal irrigation: A randomised controlled trial’, Australian endodontic journal: the journal of the Australian Society of Endodontology Inc, 41(2), pp. 78–87.
  51. Ram, D. (2007) ‘Post-operative pain and analgesic use in children’, British Dental Journal, pp. 276–277. doi: 10.1038/bdj.2007.181.
  52. Ramshankar, V. et al. (2014) ‘Risk stratification of early stage oral tongue cancers based on HPV status and p16 immunoexpression’, Asian Pacific journal of cancer prevention: APJCP, 15(19), pp. 8351–8359.
  53. Rangaswamy, S., Sheshappa, K. N. and Srikanthan, R. (2016) ‘Preemptive Analgesic Efficacy of Diclofenac Sodium for Surgical Removal of Impacted Third Molars’, Journal of Health Sciences & Research, pp. 38–41. doi: 10.5005/jp-journals-10042-1033.
  54. Rao, T. D. and Kumar, M. P. (2018) ‘Analgesic Efficacy of Paracetamol Vs Ketorolac after Dental Extractions’, Research Journal of Pharmacy and Technology, 11(8), pp. 3375–3379.
  55. Ravindiran, M. and Praveenkumar, C. (2018) ‘Status review and the future prospects of CZTS based solar cell – A novel approach on the device structure and material modeling for CZTS based photovoltaic device’, Renewable and Sustainable Energy Reviews, 94, pp. 317–329.
  56. Samuel, S. R., Acharya, S. and Rao, J. C. (2020) ‘School Interventions-based Prevention of Early-Childhood Caries among 3-5-year-old children from very low socioeconomic status: Two-year randomized trial’, Journal of public health dentistry, 80(1), pp. 51–60.
  57. Sathish, T. and Karthick, S. (2020) ‘Wear behaviour analysis on aluminium alloy 7050 with reinforced SiC through taguchi approach’, Journal of Materials Research and Technology, 9(3), pp. 3481–3487.
  58. Seymour, R. A. (1982) ‘The use of pain scales in assessing the efficacy of analgesics in post-operative dental pain’, European journal of clinical pharmacology, 23(5), pp. 441–444.
  59. Simone, J. L. et al. (2013) ‘Comparative analysis of preemptive analgesic effect of dexamethasone and diclofenac following third molar surgery’, Brazilian oral research, 27(3), pp. 266–271.
  60. Sumathi, C. et al. (2014) ‘Production of prodigiosin using tannery fleshing and evaluating its pharmacological effects’, TheScientificWorldJournal, 2014, p. 290327.
  61. Surapaneni, K. M. and Jainu, M. (2014) ‘Comparative effect of pioglitazone, quercetin and hydroxy citric acid on the status of lipid peroxidation and antioxidants in experimental non-alcoholic steatohepatitis’, Journal of physiology and pharmacology: an official journal of the Polish Physiological Society, 65(1), pp. 67–74.
  62. Surapaneni, K. M., Priya, V. V. and Mallika, J. (2014) ‘Pioglitazone, quercetin and hydroxy citric acid effect on cytochrome P450 2E1 (CYP2E1) enzyme levels in experimentally induced non alcoholic steatohepatitis (NASH)’, European review for medical and pharmacological sciences, 18(18), pp. 2736–2741.
  63. Sweta, V. R., Abhinav, R. P. and Ramesh, A. (2019) ‘Role of Virtual Reality in Pain Perception of Patients Following the Administration of Local Anesthesia’, Annals of maxillofacial surgery, 9(1), pp. 110–113.
  64. Thenarasu, V., Gurunathan, D. and Santhosh Kumar, M. P. (2018) ‘Comparison of Efficacy of Diclofenac and Paracetamol as Preemptive Analgesic Agent’, Biomedical and Pharmacology Journal, pp. 1699–1706. doi: 10.13005/bpj/1539.
  65. Vadivelu, N., Mitra, S. and Narayan, D. (2010) ‘Recent advances in postoperative pain management’, The Yale journal of biology and medicine, 83(1), p. 11.

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