Calcified carotid atherosclerotic plaque in panoramic radiographs in patients with Diabetes mellitus- A Retrospective Study
Journal of Contemporary Issues in Business and Government,
2020, Volume 26, Issue 2, Pages 1648-1658
10.47750/cibg.2020.26.02.211
Abstract
Atherosclerosis is characterized by thickening and loss of elasticity of the arterial walls, associated with the presence of atheromatous plaques.It is associated with diabetes mellitus and leads to increased risk of stroke.The aim of this study is to determine the prevalence of atherosclerotic plaques in panoramic radiograph in patients with diabetes mellitus.A retrospective study was carried out in diabetic patients who took panoramic radiographs for routine dental examination visiting Radiology department.The data were obtained from analysing 86000 patients records between June 2019-March 2020.The data comprised of 220 diabetic patients who visited Radiology department.The collected data were entered into Excel sheet and subjected to statistical analysis using SPSS software.A chi square test was done between variables.Results showed that prevalence of atheroscleerotic plaque on panoramic radiographs in patients with diabetes mellitus was found to be 34.09% . Out of 34.09%, 61.11% had unilateral atherosclerotic plaque and 38.89% had bilateral atherosclerotic plaque.Statistically significant association was found between age and presence of atherosclerotic plaque (p-value:0.014).The present study concludes that presence of atherosclerotic plaque was found highly in female diabetic patients and patients under 40-60 age group.
Main Subjects:
- Almog, D. M. et al. (2000) ‘Unrecognized carotid artery stenosis discovered by calcifications on a panoramic radiograph’, Journal of the American Dental Association , 131(11), pp. 1593–1597.
- Almog, D. M. et al. (2002) ‘Correlating carotid artery stenosis detected by panoramic radiography with clinically relevant carotid artery stenosis determined by duplex ultrasound’, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 94(6), pp. 768–773.
- Atalay, Y. et al. (2015) ‘Evaluation of calcified carotid atheroma on panoramic radiographs and Doppler ultrasonography in an older population’, Clinical interventions in aging, 10, pp. 1121–1129.
- Bayram, B. et al. (2006) ‘Digital panoramic radiography: a reliable method to diagnose carotid artery atheromas?’, Dento maxillo facial radiology, 35(4), pp. 266–270.
- Beckman, J. A., Creager, M. A. and Libby, P. (2002) ‘Diabetes and atherosclerosis: epidemiology, pathophysiology, and management’, JAMA: the journal of the American Medical Association, 287(19), pp. 2570–2581.
- Beckstrom, B. W. et al. (2007) ‘Correlation between carotid area calcifications and periodontitis: a retrospective study of digital panoramic radiographic findings in pretreatment cancer patients’, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 103(3), pp. 359–366.
- Chaitanya, N. C. et al. (2017) ‘Role of Vitamin E and Vitamin A in Oral Mucositis Induced by Cancer Chemo/Radiotherapy- A Meta-analysis’, Journal of clinical and diagnostic research: JCDR, 11(5), pp. ZE06–ZE09.
- Chaitanya, N. C. et al. (2018) ‘An Insight and Update on the Analgesic Properties of Vitamin C’, Journal of pharmacy & bioallied sciences, 10(3), pp. 119–125.
- Choudhury, P. et al. (2015) ‘Vanishing roots: first case report of idiopathic multiple cervico-apical external root resorption’, Journal of clinical and diagnostic research: JCDR, 9(3), pp. ZD17–9.
- Deogade, S., Gupta, P. and Ariga, P. (2018) ‘Effect of monopoly-coating agent on the surface roughness of a tissue conditioner subjected to cleansing and disinfection: A Contact Profilometric In vitro study’, Contemporary Clinical Dentistry, p. 122. doi: 10.4103/ccd.ccd_112_18.
- Dharman, S. and Muthukrishnan, A. (2016) ‘Oral mucous membrane pemphigoid - Two case reports with varied clinical presentation’, Journal of Indian Society of Periodontology, 20(6), pp. 630–634.
- Dua, K. et al. (2019) ‘The potential of siRNA based drug delivery in respiratory disorders: Recent advances and progress’, Drug development research, 80(6), pp. 714–730.
- Duraisamy, R. et al. (2019) ‘Compatibility of Nonoriginal Abutments With Implants: Evaluation of Microgap at the Implant-Abutment Interface, With Original and Nonoriginal Abutments’, Implant dentistry, 28(3), pp. 289–295.
- Ezhilarasan, D. (2018) ‘Oxidative stress is bane in chronic liver diseases: Clinical and experimental perspective’, Arab journal of gastroenterology: the official publication of the Pan-Arab Association of Gastroenterology, 19(2), pp. 56–64.
- Ezhilarasan, D., Apoorva, V. S. and Ashok Vardhan, N. (2019) ‘Syzygium cumini extract induced reactive oxygen species-mediated apoptosis in human oral squamous carcinoma cells’, Journal of oral pathology & medicine: official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 48(2), pp. 115–121.
- Ezhilarasan, D., Sokal, E. and Najimi, M. (2018) ‘Hepatic fibrosis: It is time to go with hepatic stellate cell-specific therapeutic targets’, Hepatobiliary & pancreatic diseases international: HBPD INT, 17(3), pp. 192–197.
- Fatahzadeh, M. and Glick, M. (2006) ‘Stroke: epidemiology, classification, risk factors, complications, diagnosis, prevention, and medical and dental management’, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 102(2), pp. 180–191.
- Friedlander, A. H. and Maeder, L. A. (2000) ‘The prevalence of calcified carotid artery atheromas on the panoramic radiographs of patients with type 2 diabetes mellitus’, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 89(4), pp. 420–424.
- Gheena, S. and Ezhilarasan, D. (2019) ‘Syringic acid triggers reactive oxygen species-mediated cytotoxicity in HepG2 cells’, Human & experimental toxicology, 38(6), pp. 694–702.
- Gomathi, A. C. et al. (2020) ‘Anticancer activity of silver nanoparticles synthesized using aqueous fruit shell extract of Tamarindus indica on MCF-7 human breast cancer cell line’, Journal of Drug Delivery Science and Technology, p. 101376. doi: 10.1016/j.jddst.2019.101376.
- Hubar, J. S. (1999) ‘Carotid artery calcification in the black population: a retrospective study on panoramic radiographs’, Dento maxillo facial radiology, 28(6), pp. 348–350.
- Jeevanandan, G. and Govindaraju, L. (2018) ‘Clinical comparison of Kedo-S paediatric rotary files vs manual instrumentation for root canal preparation in primary molars: a double blinded randomised clinical trial’, European Archives of Paediatric Dentistry, pp. 273–278. doi: 10.1007/s40368-018-0356-6.
- J, P. C. et al. (2018) ‘Prevalence and measurement of anterior loop of the mandibular canal using CBCT: A cross sectional study’, Clinical implant dentistry and related research, 20(4), pp. 531–534.
- Khambete, N. and Kumar, R. (2015) ‘Calcified carotid atherosclerotic plaques on digital panoramic radiographs in patients with Type II diabetes mellitus: A case control study’, Journal of Indian Academy of Oral Medicine and Radiology, 27(1), p. 42.
- Kumagai, M. et al. (2007) ‘Carotid artery calcification seen on panoramic dental radiographs in the Asian population in Japan’, Dento maxillo facial radiology, 36(2), pp. 92–96.
- London, G. M. et al. (2004) ‘Arterial calcifications and bone histomorphometry in end-stage renal disease’, Journal of the American Society of Nephrology: JASN, 15(7), pp. 1943–1951.
- Maheswari, T. N. U. et al. (2018) ‘Salivary micro RNA as a potential biomarker in oral potentially malignant disorders: A systematic review’, Ci ji yi xue za zhi = Tzu-chi medical journal, 30(2), pp. 55–60.
- Malli Sureshbabu, N. et al. (2019) ‘Concentrated Growth Factors as an Ingenious Biomaterial in Regeneration of Bony Defects after Periapical Surgery: A Report of Two Cases’, Case reports in dentistry, 2019, p. 7046203.
- Mathew, M. G. et al. (2020) ‘Evaluation of adhesion of Streptococcus mutans, plaque accumulation on zirconia and stainless steel crowns, and surrounding gingival inflammation in primary …’, Clinical oral investigations. Available at: https://link.springer.com/article/10.1007/s00784-020-03204-9.
- Mehta, M. et al. (2019) ‘Oligonucleotide therapy: An emerging focus area for drug delivery in chronic inflammatory respiratory diseases’, Chemico-biological interactions, 308, pp. 206–215.
- Menon, S. et al. (2018) ‘Selenium nanoparticles: A potent chemotherapeutic agent and an elucidation of its mechanism’, Colloids and Surfaces B: Biointerfaces, pp. 280–292. doi: 10.1016/j.colsurfb.2018.06.006.
- Misra, S. R. et al. (2015) ‘Metastatic hepatocellular carcinoma in the maxilla and mandible, an extremely rare presentation’, Contemporary clinical dentistry, 6(Suppl 1), pp. S117–21.
- Muthukrishnan, A. and Bijai Kumar, L. (2017) ‘Actinic cheilosis: early intervention prevents malignant transformation’, BMJ case reports, 2017. doi: 10.1136/bcr-2016-218654.
- Muthukrishnan, A., Bijai Kumar, L. and Ramalingam, G. (2016) ‘Medication-related osteonecrosis of the jaw: a dentist’s nightmare’, BMJ case reports, 2016. doi: 10.1136/bcr-2016-214626.
- Muthukrishnan, A. and Warnakulasuriya, S. (2018) ‘Oral health consequences of smokeless tobacco use’, The Indian journal of medical research, 148(1), pp. 35–40.
- Panchal, V., Jeevanandan, G. and Subramanian, E. M. G. (2019) ‘Comparison of post-operative pain after root canal instrumentation with hand K-files, H-files and rotary Kedo-S files in primary teeth: a randomised clinical trial’, European archives of paediatric dentistry: official journal of the European Academy of Paediatric Dentistry, 20(5), pp. 467–472.
- Patil, S. R. et al. (2018) ‘Three-Rooted Mandibular First Molars in a Saudi Arabian Population: A CBCT Study’, Pesquisa brasileira em odontopediatria e clinica integrada, 18(1), p. 4133.
- Pc, J., Marimuthu, T. and Devadoss, P. (2018) ‘Prevalence and measurement of anterior loop of the mandibular canal using CBCT: A cross sectional study’, Clinical implant dentistry and related research. Available at: https://europepmc.org/article/med/29624863.
- Prabakar, J. et al. (2018) ‘Comparative Evaluation of Retention, Cariostatic Effect and Discoloration of Conventional and Hydrophilic Sealants - A Single Blinded Randomized Split Mouth Clinical Trial’, Contemporary clinical dentistry, 9(Suppl 2), pp. S233–S239.
- Rajendran, R. et al. (2019) ‘Comparative Evaluation of Remineralizing Potential of a Paste Containing Bioactive Glass and a Topical Cream Containing Casein Phosphopeptide-Amorphous Calcium Phosphate: An in Vitro Study’, Pesquisa Brasileira em Odontopediatria e Clínica Integrada, pp. 1–10. doi: 10.4034/pboci.2019.191.61.
- Rajeshkumar, S. et al. (2018) ‘Biosynthesis of zinc oxide nanoparticles usingMangifera indica leaves and evaluation of their antioxidant and cytotoxic properties in lung cancer (A549) cells’, Enzyme and microbial technology, 117, pp. 91–95.
- Rajeshkumar, S. et al. (2019) ‘Antibacterial and antioxidant potential of biosynthesized copper nanoparticles mediated through Cissus arnotiana plant extract’, Journal of photochemistry and photobiology. B, Biology, 197, p. 111531.
- Ramadurai, N. et al. (2019) ‘Effectiveness of 2% Articaine as an anesthetic agent in children: randomized controlled trial’, Clinical oral investigations, 23(9), pp. 3543–3550.
- Ramakrishnan, M., Dhanalakshmi, R. and Subramanian, E. M. G. (2019) ‘Survival rate of different fixed posterior space maintainers used in Paediatric Dentistry - A systematic review’, The Saudi dental journal, 31(2), pp. 165–172.
- Ramesh, A. et al. (2018) ‘Comparative estimation of sulfiredoxin levels between chronic periodontitis and healthy patients - A case-control study’, Journal of periodontology, 89(10), pp. 1241–1248.
- Rohini, S. and Kumar, V. J. (2017) ‘Incidence of dental caries and pericoronitis associated with impacted mandibular third molar-A radiographic study’, Research Journal of Pharmacy and Technology, 10(4), pp. 1081–1084.
- Roldán-Chicano, R. et al. (2006) ‘Panoramic radiograph as a method for detecting calcified atheroma plaques. Review of literature’, Medicina oral, patologia oral y cirugia bucal, 11(3), pp. E261–6.
- Samuel, S. R., Acharya, S. and Rao, J. C. (2020) ‘School Interventions-based Prevention of Early-Childhood Caries among 3-5-year-old children from very low socioeconomic status: Two-year randomized trial’, Journal of public health dentistry, 80(1), pp. 51–60.
- Sharma, P. et al. (2019) ‘Emerging trends in the novel drug delivery approaches for the treatment of lung cancer’, Chemico-biological interactions, 309, p. 108720.
- Sridharan, G. et al. (2019) ‘Evaluation of salivary metabolomics in oral leukoplakia and oral squamous cell carcinoma’, Journal of oral pathology & medicine: official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 48(4), pp. 299–306.
- Steele, J. C. et al. (2015) ‘World Workshop on Oral Medicine VI: an international validation study of clinical competencies for advanced training in oral medicine’, Oral surgery, oral medicine, oral pathology and oral radiology, 120(2), pp. 143–51.e7.
- Subashri, A. and Maheshwari, T. N. (2016) ‘Knowledge and attitude of oral hygiene practice among dental students’, Research Journal of Pharmacy and Technology, 9(11), pp. 1840–1842.
- Subha, M. and Arvind, M. (2019) ‘Role of magnetic resonance imaging in evaluation of trigeminal neuralgia with its anatomical correlation’, Biomedical and Pharmacology Journal, 12(1), pp. 289–296.
- Tofangchiha, M. et al. (2011) ‘The carotid artery calcification in type II diabetic patients on panoramic radiographs: An important marker for vascular risk’, Scientific Research and Essays, 6(31), pp. 6548–6553.
- Varghese, S. S., Ramesh, A. and Veeraiyan, D. N. (2019) ‘Blended Module-Based Teaching in Biostatistics and Research Methodology: A Retrospective Study with Postgraduate Dental Students’, Journal of dental education, 83(4), pp. 445–450.
- Venugopal, A. and Uma Maheswari, T. N. (2016) ‘Expression of matrix metalloproteinase-9 in oral potentially malignant disorders: A systematic review’, Journal of oral and maxillofacial pathology: JOMFP, 20(3), pp. 474–479.
- Vijayashree Priyadharsini, J. (2019) ‘In silico validation of the non-antibiotic drugs acetaminophen and ibuprofen as antibacterial agents against red complex pathogens’, Journal of periodontology, 90(12), pp. 1441–1448.
- Vishnu Prasad, S. et al. (2018) ‘Report on oral health status and treatment needs of 5-15 years old children with sensory deficits in Chennai, India’, Special care in dentistry: official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry, 38(1), pp. 58–59.
- Wahab, P. U. A. et al. (2018) ‘Scalpel Versus Diathermy in Wound Healing After Mucosal Incisions: A Split-Mouth Study’, Journal of oral and maxillofacial surgery: official journal of the American Association of Oral and Maxillofacial Surgeons, 76(6), pp. 1160–1164.
- Yoon, S.-J. et al. (2008) ‘Diagnostic accuracy of panoramic radiography in the detection of calcified carotid artery’, Dento maxillo facial radiology, 37(2), pp. 104–108.
- Zhdanov, V. S. and Sternby, N. H. (2004) ‘Monitoring of atherosclerosis’, International journal of cardiology, 95(1), pp. 39–42.
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